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1

Mechanistic Studies on Histone Catalyzed Cleavage of Apyrimidinic/Apurinic Sites in Nucleosome Core Particles

Zhou, Chuanzheng, Sczepanski, Jonathan T., Greenberg, Marc M.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 3.34 MB

english, 2012

2

Fine Tuning of Electrostatics around the Internucleotidic Phosphate through Incorporation of Modified 2′,4′-Carbocyclic-LNAs and -ENAs Leads to Significant Modulation of Antisense Properties

Zhou, Chuanzheng, Liu, Yi, Andaloussi, Mounir, Badgujar, Naresh, Plashkevych, Oleksandr, Chattopadhyaya, Jyoti

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 5.09 MB

english, 2009

3

Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones

Zhang, Yingqian, Zang, Chuanlong, An, Guoce, Shang, Mengdi, Cui, Zenghui, Chen, Gong, Xi, Zhen, Zhou, Chuanzheng

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 1.46 MB

english, 2020

4

ChemInform Abstract: Synthesis and Structure of New Methylene-Bridged Hexopyranosyl Nucleoside (BHNA).

Chuanzheng Zhou, Oleksandr Plashkevych, Yi Liu, Naresh Badgujar, Jyoti Chattopadhyaya

Journal:

Year:

2009

File:

PDF, 26 KB

2009

5

ChemInform Abstract: The Synthesis of Therapeutic Locked Nucleos(t)ides

Chuanzheng Zhou, Jyoti Chattopadhyaya

Journal:

Year:

2010

File:

PDF, 12 KB

2010

6

A thermostable azo-linker for reversible photoregulation of DNA replication

Qi Wang, Long Yi, Liangliang Liu, Chuanzheng Zhou, Zhen Xi

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 414 KB

english, 2008

7

ChemInform Abstract: Intramolecular Free-Radical Cyclization Reactions on Pentose Sugars for the Synthesis of Carba-LNA and Carba-ENA and the Application of Their Modified Oligonucleotides as Potential RNA Targeted Therapeutics

Chuanzheng Zhou, Jyoti Chattopadhyaya

Journal:

Year:

2012

File:

PDF, 18 KB

2012

8

Unusual radical 6-endo cyclization to carbocyclic-ENA and elucidation of its solution conformation by 600 MHz NMR and ab initio calculations

Zhou, Chuanzheng, Plashkevych, Oleksandr, Chattopadhyaya, Jyoti

Journal:

Organic & Biomolecular Chemistry

Year:

2008

Language:

english

File:

PDF, 339 KB

english, 2008

9

Non-identical electronic characters of the internucleotidic phosphates in RNA modulate the chemical reactivity of the phosphodiester bonds

Barman, Jharna, Acharya, Sandipta, Zhou, Chuanzheng, Chatterjee, Subhrangsu, Engström, Åke, Chattopadhyaya, Jyoti

Journal:

Organic & Biomolecular Chemistry

Year:

2006

Language:

english

File:

PDF, 481 KB

english, 2006

10

Synthesis of 2′,4′-Propylene-Bridged (Carba-ENA) Thymidine and Its Analogues: The Engineering of Electrostatic and Steric Effects at the Bottom of the Minor Groove for Nuclease and Thermodynamic Stabilities and Elicitation of RNase H

Liu, Yi, Xu, Jianfeng, Karimiahmadabadi, Mansoureh, Zhou, Chuanzheng, Chattopadhyaya, Jyoti

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 4.63 MB

english, 2010

11

Histone-Catalyzed Cleavage of Nucleosomal DNA Containing 2-Deoxyribonolactone

Zhou, Chuanzheng, Greenberg, Marc M.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

12

Histone Modification via Rapid Cleavage of C4′-Oxidized Abasic Sites in Nucleosome Core Particles

Zhou, Chuanzheng, Sczepanski, Jonathan T., Greenberg, Marc M.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

13

DNA Damage by Histone Radicals in Nucleosome Core Particles

Zhou, Chuanzheng, Greenberg, Marc M.

Journal:

Journal of the American Chemical Society

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

14

Intramolecular Free-Radical Cyclization Reactions on Pentose Sugars for the Synthesis of Carba-LNA and Carba-ENA and the Application of Their Modified Oligonucleotides as Potential RNA Targeted Therapeutics

Zhou, Chuanzheng, Chattopadhyaya, Jyoti

Journal:

Chemical Reviews

Year:

2012

Language:

english

File:

PDF, 9.32 MB

english, 2012

15

Three-dimensional velocity field of present-day crustal motion of the Tibetan Plateau derived from GPS measurements

Liang, Shiming, Gan, Weijun, Shen, Chuanzheng, Xiao, Genru, Liu, Jing, Chen, Weitao, Ding, Xiaoguang, Zhou, Deming

Journal:

Journal of Geophysical Research Solid Earth

Year:

2013

Language:

english

File:

PDF, 4.89 MB

english, 2013

16

Free-Radical Ring Closure to Conformationally Locked α- l -Carba-LNAs and Synthesis of Their Oligos: Nuclease Stability, Target RNA Specificity, and Elicitation of RNase H

Li, Qing, Yuan, Fengfeng, Zhou, Chuanzheng, Plashkevych, Oleksandr, Chattopadhyaya, Jyoti

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 6.06 MB

english, 2010

17

Double Sugar and Phosphate Backbone-Constrained Nucleotides: Synthesis, Structure, Stability, and Their Incorporation into Oligodeoxynucleotides

Zhou, Chuanzheng, Plashkevych, Oleksandr, Chattopadhyaya, Jyoti

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 4.16 MB

english, 2009

18

Nucleosome Core Particle-Catalyzed Strand Scission at Abasic Sites

Sczepanski, Jonathan T., Zhou, Chuanzheng, Greenberg, Marc M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.47 MB

english, 2013

19

Why Carba-LNA-Modified Oligonucleotides Show Considerably Improved 3′-Exonuclease Stability Compared to That of the LNA Modified or the Native Counterparts: A Michaelis−Menten Kinetic Analysis

Zhou, Chuanzheng, Chattopadhyaya, Jyoti

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 1.76 MB

english, 2010

20

Modulation of Pyrene Fluorescence in DNA Probes Depends upon the Nature of the Conformationally Restricted Nucleotide

Honcharenko, Dmytro, Zhou, Chuanzheng, Chattopadhyaya, Jyoti

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 500 KB

english, 2008

21

High-quality oligo-RNA synthesis using the new 2′- O- TEM protecting group by selectively quenching the addition of p- tolyl vinyl sulphone to exocyclic amino functions

Zhou, Chuanzheng, Pathmasiri, Wimal, Honcharenko, Dmytro, Chatterjee, Subhrangsu, Barman, Jharna, Chattopadhyaya, Jyoti

Journal:

Canadian Journal of Chemistry

Year:

2007

File:

PDF, 540 KB

2007

22

Probing Interactions between Lysine Residues in Histone Tails and Nucleosomal DNA via Product and Kinetic Analysis

Weng, Liwei, Zhou, Chuanzheng, Greenberg, Marc M.

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 432 KB

english, 2015

23

In vivo efficacy and off-target effects of Locked Nucleic Acid (LNA) and Unlocked Nucleic Acid (UNA) modified siRNA and small internally segmented interfering RNA (sisiRNA) in mice bearing human tumor xenografts

Mook, O.R., Vreijling, Jeroen, Wengel, Suzy, Wengel, Jesper, Zhou, Chuanzheng, Chattopadhyaya, Jyoti, Baas, Frank, Fluiter, Kees

Journal:

Artificial DNA PNA & XNA

Year:

2010

Language:

english

File:

PDF, 1.56 MB

english, 2010

24

Thiol Specific and Tracelessly Removable Bioconjugation via Michael Addition to 5-Methylene Pyrrolones

Zhang, Yingqian, Zhou, Xiaoping, Xie, Yonghui, Greenberg, Marc M., Xi, Zhen, Zhou, Chuanzheng

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 767 KB

english, 2017

25

5-Formylcytosine Yields DNA–Protein Cross-Links in Nucleosome Core Particles

Li, Fengchao, Zhang, Yingqian, Bai, Jing, Greenberg, Marc M., Xi, Zhen, Zhou, Chuanzheng

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

26

Synthesis and Biological Applications of Fluoro-Modified Nucleic Acids

Guo, Fengmin, Li, Qiang, Zhou, Chuanzheng

Journal:

Organic & Biomolecular Chemistry

Year:

2017

Language:

english

File:

PDF, 1.39 MB

english, 2017

27

Coffee consumption and risk of esophageal cancer incidence

Zhang, Juan, Zhou, Bin, Hao, Chuanzheng

Journal:

Medicine (Medicine Publishing Company Ltd)

Year:

2018

Language:

english

File:

PDF, 411 KB

english, 2018

28

Effect of Ribose Conformation on RNA Cleavage via Internal Transesterification

Guo, Fengmin, Yue, Zekun, Trajkovski, Marko, Zhou, Xiaoping, Cao, Dong, Li, Qiang, Wang, Baifan, Wen, Xin, Plavec, Janez, Peng, Qian, Xi, Zhen, Zhou, Chuanzheng

Journal:

Journal of the American Chemical Society

Year:

2018

Language:

english

File:

PDF, 510 KB

english, 2018

29

Oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine leads to substantial DNA-histone cross-links within nucleosome core particles

Bai, Jing, Zhang, Yingqian, Xi, Zhen, Greenberg, Marc M., Zhou, Chuanzheng

Journal:

Chemical Research in Toxicology

Year:

2018

Language:

english

File:

PDF, 542 KB

english, 2018

30

Lipoxin A4 receptor agonist BML-111 induces autophagy in alveolar macrophages and protects from acute lung injury by activating MAPK signaling

Liu, Huaizheng, Zhou, Kefu, Liao, Liangkan, Zhang, Tianyi, Yang, Mingshi, Sun, Chuanzheng

Journal:

Respiratory Research

Year:

2018

Language:

english

File:

PDF, 3.78 MB

english, 2018

31

4′-C-Trifluoromethyl modified oligodeoxynucleotides: synthesis, biochemical studies, and cellular uptake properties

Zhou, Yifei, Zang, Chuanlong, Wang, Huawei, Li, Jiajun, Cui, Zenghui, Li, Qiang, Guo, Fengmin, Yan, Zhiguo, Wen, Xin, Xi, Zhen, Zhou, Chuanzheng

Journal:

Organic & Biomolecular Chemistry

Year:

2019

Language:

english

File:

PDF, 2.41 MB

english, 2019

32

4′-C-Trifluoromethyl modified oligodeoxynucleotides: synthesis, biochemical studies, and cellular uptake properties

Zhou, Yifei, Zang, Chuanlong, Wang, Huawei, Li, Jiajun, Cui, Zenghui, Li, Qiang, Guo, Fengmin, Yan, Zhiguo, Wen, Xin, Xi, Zhen, Zhou, Chuanzheng

Journal:

Organic & Biomolecular Chemistry

Year:

2019

File:

PDF, 2.41 MB

2019

33

Formation and biological consequences of 5-Formylcytosine in genomic DNA

Zhang, Yingqian, Zhou, Chuanzheng

Journal:

Year:

2019

Language:

english

File:

PDF, 1.85 MB

english, 2019

34

A light-responsive, self-immolative linker for controlled drug delivery via peptide- and protein-drug conjugates

Zang, Chuanlong, Wang, Huawei, Li, Tiantian, Zhang, Yingqian, Li, Jiahui, Shang, Mengdi, Du, Juanjuan, Xi, Zhen, Zhou, Chuanzheng

Journal:

Chemical Science

Year:

2019

File:

PDF, 1.19 MB

2019

35

A Nitrogen Mustard Induces Formation of DNA–Histone Cross-Links in Nucleosome Core Particles

Shang, Mengdi, Ren, Mengtian, Zhou, Chuanzheng

Journal:

Chemical Research in Toxicology

Year:

2019

Language:

english

File:

PDF, 556 KB

english, 2019

36

Long noncoding RNA CCAT1 inhibits miRâ613 to promote nonalcoholic fatty liver disease via increasing LXRÎ± transcription

Huang, Feizhou, Liu, Huaizheng, Lei, Zhao, Li, Zhenzhou, Zhang, Tianyi, Yang, Mingshi, Zhou, Kefu, Sun, Chuanzheng

Journal:

Journal of Cellular Physiology

Year:

2020

File:

PDF, 3.44 MB

2020

37

Jason-1 Observation of Typhoon Storm Surge and Analysis Based on Numerical Simulation

Qiu, Zhou, Zheng, Gang, Yang, Jingsong, Han, Guoqi, Li, Xiaohui, Zhang, Chuanzheng, Zhou, Lizhang, Wang, Yan

Journal:

IOP Conference Series Materials Science and Engineering

Year:

2020

File:

PDF, 954 KB

2020

38

Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS)

Wang, Huawei, Zang, Chuanlong, Ren, Mengtian, Shang, Mengdi, Wang, Zhenghua, Peng, Xuemei, Zhang, Qiangzhe, Wen, Xin, Xi, Zhen, Zhou, Chuanzheng

Journal:

Scientific Reports

Year:

2020

File:

PDF, 2.60 MB

2020